探索ENCODE数据库 | Encyclopedia of DNA Elements

ENCODE: Encyclopedia of DNA Elements

目标：按不同组织，收集人类（还有小鼠、worm、fly）基因组里面的所有功能元件

The primary goal of the ENCODE project is to determine the role of the remaining component of the genome, much of which was traditionally regarded as "junk."

所包含的数据：

文件检索和下载：

Getting Started - 教程

ENCODE Experiment Matrix - 总览ENCODE有哪些数据

检索过滤下载页面

如果想下载所有细胞系合并后的数据，可以看LDSC这个工具里面的数据库。

LDSC paper：Partitioning heritability by functional annotation using genome-wide association summary statistics

数据库地址

baseline_v1.1_bedfiles.tgz

相关项目：

Roadmap Epigenomics Project

The Consortium leverages experimental pipelines built around next-generation sequencing technologies to map DNA methylation, histone modifications, chromatin accessibility and small RNA transcripts in stem cells and primary ex vivo tissues selected to represent the normal counterparts of tissues and organ systems frequently involved in human disease.

待续~