There is a known issue in Windows 10 Insider Preview build 10074 (see here).

The current work around is enabling developer mode via group policy editor or register editor.

How to enable your device for development using the Group Policy Editor

If you use Visual Studio on a Windows 10 desktop and you open a solution for a Windows 8.1 or Windows 10 app, you will be prompted to enable your device with this dialog. (You also need your device to be enabled to use the designers and debug your app.)

When you see this dialog, click OK. Then follow the steps below to enable your desktop from Windows 10 Insider Preview.

For Windows 10 desktop

Use gpedit.msc to set the group policies to enable your device, unless you have Windows 10 Insider Preview Home Edition. If you do have Home Edition, you need to use regedit or PowerShell commands to set the registry keys directly to enable your device.

Use gpedit to enable your device

  1. Open a cmd prompt with administrator privileges.
  2. Run Gpedit.msc.
  3. Go to Local Computer Policy > Computer Configuration > Administrative Templates > Windows Components > App Package Deployment
  4. Edit the policies to enable the following:
    • Allow all trusted apps to install (Enables your device for sideloading apps)
    • Allows development of Windows Store apps and installing them from an integrated development environment (IDE) (Enables your device for development from Visual Studio)
  5. Reboot your machine.

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