Windows Server 2008 MS Office 操作 检索 COM 类工厂中 CLSID 为 {00024500-0000-0000-C000-000000000046} 的组件失败，原因是出现以下错误: 80070005 拒绝访问。 (异常来自 HRESULT:0x80070005 (E_ACCESSDENIED))。

1. Make sure that you have Office runtime installed on the server.
2. If you are using Windows Server 2008 then using office interops is a lenghty configuration and here are the steps.

Better is to move to Open XML or you can configure as below

• Install MS Office Pro Latest (I used 2010 Pro)
• Create User ExcelUser. Assign WordUser with Admin Group
• Go to Computer -> Manage
• Add User with below options
• User Options Password Never Expires
• Password Cannot Be Change

Com+ Configuration

• Go to Control Panel - > Administrator -> Component Services -> DCOM Config
• Open Microsoft Word 97 - 2003 Properties
• General -> Authentication Level : None
• Security -> Customize all 3 permissions to allow everyone
• Identity -> This User -> Use ExcelUser /password
• Launch the Excel App to make sure everything is fine

3.Change the security settings of Microsoft Excel Application in DCOM Config.

Controlpanel --> Administrative tools-->Component Services -->computers --> myComputer -->DCOM Config --> Microsoft Excel Application.

Right click to get properties dialog. Go to Security tab and customize permissions