Chip-seq peak annontation Chip-seq peak annontation PeRl narrowPeak/boardPeak narrowPeak/boardPeak 是ENCODE可提供下载的两种 Chip-seq 经过参考人类基因组mapping后的关于peak的数据. 其他类型的seq数据储存个数可以参看FAQformat narrowPeak 数据按照以下规则储存: 1. string chrom: "Reference sequence chromosom…

总是跑数据,却对数据一无所知,这说不过去吧. 看几篇文章吧 Sequencing depth and coverage: key considerations in genomic analyses(只讲二代) Assembly of large genomes using second-generation sequencing(参考文献) Identification of optimum sequencing depth especially for de novo genome asse…

getopt的两个模块getopt和gun_getopt都可以接收参数,但是又有不同; 先看 getopt.getopt这个模块: import sys import getopt def main(param): opts, args = getopt.getopt(param,"hc:s:") print("opts",opts ) print("args",args) for opt,arg in opts: if opt == "…

大家好,这里是专注表观组学十余年,多组学科研服务领跑者的易基因. 染色质免疫沉淀后测序(ChIP seq)是一种针对DNA结合蛋白.组蛋白修饰或核小体的全基因组分析技术.由于二代测序技术的巨大进步,ChIP-seq比其最初版本ChIP-chip具有更高的分辨率.更低的噪声和更大的覆盖范围.随着测序成本的降低,ChIP- seq已成为研究基因调控和表观遗传机制不可或缺的工具. 原理:甲醛处理细胞使目标蛋白与DNA交联,通过超声波将交联后的染色质打断成小片段,一般在200-600bp范围内.再利用抗…

A peak element is an element that is greater than its neighbors. Given an input array where num[i] ≠ num[i+1], find a peak element and return its index. The array may contain multiple peaks, in that case return the index to any one of the peaks is fi…

Problem: A peak element is an element that is greater than its neighbors. Given an input array where num[i] ≠ num[i+1], find a peak element and return its index. The array may contain multiple peaks, in that case return the index to any one of the pe…

A peak element is an element that is greater than its neighbors. Given an input array where num[i] ≠ num[i+1], find a peak element and return its index. The array may contain multiple peaks, in that case return the index to any one of the peaks is fi…

There is an integer array which has the following features: The numbers in adjacent positions are different. A[0] < A[1] && A[A.length - 2] > A[A.length - 1]. We define a position P is a peek if: A[P] > A[P-1] && A[P] > A[P+1]…

1798: [Ahoi2009]Seq 维护序列seq Time Limit: 30 Sec  Memory Limit: 64 MBSubmit: 5504  Solved: 1937[Submit][Status][Discuss] Description 老师交给小可可一个维护数列的任务,现在小可可希望你来帮他完成. 有长为N的数列,不妨设为a1,a2,…,aN .有如下三种操作形式: (1)把数列中的一段数全部乘一个值; (2)把数列中的一段数全部加一个值; (3)询问数列中的一段数的和…

COMPUTER OR GANIZATION AND ARCHITECTURE DESIGNING FOR PERFORMANCE NINTH EDITION A multicore computer, also known as a chip multiprocessor, combines two or more processors (called cores) on a single piece of silicon (called a die). Typically, each cor…