The Kaplan–Meier estimator (also known as the product limit estimator) estimates the survival function from life-time data. In medical research, it might be used to measure the fraction of patients living for a certain amount of time after treatment.
虽然我们现在完全没有甲基化的数据,但还是可以了解一下. 什么是DNA甲基化,与组蛋白修饰有什么联系? DNA Methylation and Its Basic Function 表观的定义就是DNA序列不变.表型变了.最重要的就是DNA的修饰(甲基化)和组蛋白的修饰(chip-seq里面的那几种) 为什么说甲基化比SNP在早筛方面要靠谱得多? DNA甲基化测序的基本原理?Bisulfite Treatment,会特异的改变原来的甲基化和非甲基化的序列,无甲基化的C全部变为U. Pan-Canc
The top 100 papers Nature explores the most-cited research of all time. The discovery of high-temperature superconductors, the determination of DNA’s double-helix structure, the first observations that the expansion of the Universe is accelerating —
https://github.com/Jialab-UCR/GDCRNATools GDCRNATools - An R package for downloading, organizing, and integrative analyzing lncRNA, mRNA, and miRNA data in GDC Introduction The Genomic Data Commons (GDC) maintains standardized genomic, clinical, and